SABER UCV >
1) Investigación >
Artículos Publicados >
Por favor, use este identificador para citar o enlazar este ítem:
http://hdl.handle.net/10872/14421
|
| Título : | Helper Activity by Human Large Granular Lymphocytes in in Vitro Immunoglobulin Synthesis |
| Autor : | Rodriguez, Martin A.
Blanca, Isaac
Baroja, Miren L.
Arama, Simy
Leon-Ponte, Matilde
Abadí, Isaac
Bianco Colmenares, Nicolás E. |
| Palabras clave : | Large granular lymphocytes
B lymphocytes
immunoglobulin synthesis
helper Iymphocyte function
mitogen-activated
LGL |
| Fecha de publicación : | 1987 |
| Editorial : | Journal of Clinical lmmunology |
| Citación : | Vol. 7;No. 5 pp 356-364 |
| Resumen : | In the present study we have examined the effect of human large granular Iymphocytes (LGL) from health y donors on Ig synthesis by autologous B Iymphocytes. The results showed that this cell population has a consistent helper activity in pokeweed mitogen-activated cultures even when added at very low numbers. LGL can mediate their effect by secreting soluble helper factors capable of modulating B-cell responses as evidenced by the enhancement of IgG and IgM production by supernatants obtained from LGL cultures. Preincubation with interferon gamma further potentiated the helper activity by LGL. |
| URI : | http://hdl.handle.net/10872/14421 |
| ISSN : | 1573-2592 |
| Aparece en las colecciones: | Artículos Publicados
|
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.
|
