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http://hdl.handle.net/10872/14533
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Título : | First Description of Endemic HTLV-II Infection Among Venezuelan Amerindians |
Autor : | Echeverria de Perez, Gloria Leon-Ponte, Matilde Noya, Oscar Botto, Carlos Gallo, Dana BIANCO COLMENARES, NICOLÁS E. |
Palabras clave : | HTLV-II Amerindians Pume Yaruro enzyme immunoassays infected cell |
Fecha de publicación : | 1993 |
Editorial : | Journal of Acquired Immune Deficiency Syndromes |
Citación : | Vol. 6;No. 12 pp 1368-1372 |
Resumen : | We describe for the first time the presence of human T lymphotropic virus type II (HTLV-II) infection in Venezuela, among the Pume Amerindians living in the southern plains of the country. Antibodies to HTLV-II antigens were assessed by enzyme immunoassays (Elisa), Western blot, radioimmuno-precipitation, and immunofluorescence; titration studies against HTLV-I- and HTLV-II-infected cell lines were very useful in the differentiation of HTLV-I and HTLV-II antibodies. The HTLV-II general prevalence was 5%; however, there is a striking difference in prevalence between the truly isolated villages (0%) when compared to those living along the riverside and thus in contact with outsiders (9%). Preliminary evidence suggests sexual contact as the main source of transmission. These findings might suggest that HTLV-II in Venezuela originated through contact with outsiders rather than ancient infection related to the origins of the Pume. |
URI : | http://hdl.handle.net/10872/14533 |
ISSN : | 1525-4135 |
Aparece en las colecciones: | Artículos Publicados
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