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http://hdl.handle.net/10872/14843
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Título : | Endemic infection with HTLV-IIB in Venezuelan Indians: molecular characterization. |
Autor : | Leon-Ponte, Matilde Echeverria de Perez, Gloria Bianco Colmenares, Nicolás E. Hengst, James Dube, Syamalima Lave, Jayne |
Palabras clave : | HTLV-IIB Endemic infection Venezuelan Indians peripheral blood Molecular Characterization HTLV-II NRA |
Fecha de publicación : | 1998 |
Editorial : | Journal of acquired immune deficiency syndromes and human retrovirology |
Citación : | Vol. 17;No. 5 pp 458-464 |
Resumen : | The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA. |
URI : | http://hdl.handle.net/10872/14843 |
ISSN : | 1077-9450 |
Aparece en las colecciones: | Artículos Publicados
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