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http://hdl.handle.net/10872/2363
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Título : | Plasmid-encoded resistance to arsenic compounds in Gram-negative bacteria isolated from a hospital environment in Venezuela1 |
Autor : | Pedroza, Raquel Ramirez, Alvaro Alonso, Guillermina Rodriguez, Vidal |
Palabras clave : | Plasmids Amikac:in Arsenite R factors Incompatibility Rep probes |
Fecha de publicación : | 14-Jan-2013 |
Resumen : | Resistance to arsenic compounds was examined among amikacin resistant Gram-negative bacteria isolate from a hospital environment. Arsenite resist,lnce (Ars’) was found in a high proportion of isolates ( > 60%) being frequently associated with
resistance to tellurite (40%), and to other antimicrobial agents. Ars determinants (27%) were found to be transferable to E. coli
K12 strains from which large plasmid DNA molecules were isolated and characterized by agarose gel electrophoresis. Plasmids
were identified by both classical incompatibility tests, and by replicon typing using DNA specific probes. Most of the
amikacin-arsenite (AkkArsIl conjugative plasmids belong to the H incompatibility group. These results suggest that Ak-Ars
resistance linked to IncH plasmids is wide spread in Gram-negative bacteria. 0 1997 Elsevier Science B.V. |
URI : | http://hdl.handle.net/10872/2363 |
Aparece en las colecciones: | Artículos Publicados
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