Curable sexually transmitted infections among female sex workers in a population of Zulia State, Venezuela

Autores/as

  • Nailet Arráiz School of Bioanalysis. Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • María P. Sánchez School of Bioanalysis. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Valmore Bermúdez Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Baldimiro Urdaneta School of Bioanalysis. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Carem Prieto Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Carolina Escalona Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Andrea Mujica Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.
  • Endrina Mujica Molecular Biology Research Laboratory of Research Center for Endocrine-Metabolic Diseases. Faculty of Medicine, University of Zulia. Maracaibo, Zulia State.

Palabras clave:

Curable STIs, Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum, female sex workers, cervicitis, PCR, ITS curables, trabajadoras sexuales, cervicitis.

Resumen

Abstract: Sexually transmitted infections (STIs) represent a public health problem worldwide. The aim of this study was to investigate the prevalence of curable STIs caused by Neisseria gonorrhoeae, Chlamydia trachomatis and Ureaplasma urealyticum in female sex workers in a population from Zulia State, Venezuela. Seventy eight (78) women attended a health monitoring sanitary controls were evaluated, and PCR amplification assays were used to detect the three microorganisms in endocervical samples. In 33.3% of the samples, at least one microorganism was detected: U. urealyticum was found more frequently (25.6%), followed by N. gonorrhoeae (18%), and C. trachomatis (12.8%). A significant association between N. gonorrhoeae and C. trachomatis was found (p <0.0001). STIs cases represented 42.9% and 28% for symptomatic and asymptomatic groups, respectively. In the symptomatic group, N. gonorrhoeae was 2.4 times (28.6%) more frequent than in the asymptomatic one (12%) (p=0.015), particularly associated with mucopurulent discharge (p=0.025). No association was found between C. trachomatis (p=0.078), and U. urealyticum (p=0.432) with clinical manifestations. Prevalence of curable STIs in the study population was relatively low compared with other high-risk populations worldwide. The results support the possible association between C. trachomatis and N. gonorrhoeae, therefore, treatment would be indicated against both pathogens when one of them is detected in vulnerable populations.

Infecciones de transmisión sexual curables en trabajadoras sexuales en una población del estado Zulia, Venezuela

Resumen: Las infecciones de transmisión sexual (ITS) representan un problema de salud pública a nivel mundial. El objetivo de este estudio fue investigar la prevalencia de ITS curables causadas por Neisseria gonorrhoeae, Chlamydia trachomatis y Ureaplasma urealyticum en trabajadoras sexuales de una población del estado Zulia, Venezuela. Se evaluaron 78 mujeres que asistieron a jornadas de control sanitario y se utilizaron ensayos de amplificación por PCR para detectar los tres microorganismos en muestras endocervicales. En 33,3% de las muestras, se detectó al menos un microorganismo: U. urealyticum fue encontrado con mayor frecuencia (25,6%), seguido de N.gonorrhoeae (18%) y C. trachomatis (12,8%). Se encontró asociación significativa entre N. gonorrhoeae y C. trachomatis (p<0,0001). Los casos de ITS representaron porcentajes de 42% y 28% para los grupos sintomático y asintomático, respectivamente. N. gonorrhoeae fue 2,4 veces más frecuente en el grupo sintomático (28,6%) que en el asintomático (12%) (p=0,015), particularmente asociado con secreción mucopurulenta (p=0,025). No se encontró asociación entre C. trachomatis (p=0,078) y U. urealyticum (p=0,432) con manifestaciones clínicas. La prevalencia de ITS de la población en estudio fue relativamente baja comparada con otras poblaciones de alto riesgo a nivel mundial. Los resultados apoyan la posible asociación entre C. trachomatis y N. gonorrhoeae, por lo tanto se debería considerar el tratamiento contra ambos patógenos, cuando uno de ellos sea detectado en poblaciones vulnerables.

Descargas

Los datos de descargas todavía no están disponibles.

Descargas

Número

Sección

Artículos originales